Table Table 1.
Summary of Pathways for rLOX‐PP Uptake.
| Cell Line | Minor pathways | Major pathways | ||
|---|---|---|---|---|
| Dynamin‐dependent uptake | Dynamin‐independent macropinocytosis | |||
| Clathrin (Dynasore) | Caveolae (Caveolin‐1 siRNA) | Actin (Cytochalasin D) | PI3K (LY294002) | |
| PWR‐1E | + | + | + | |
| DU145 | +++ | |||
| PC3 | + | +++ | + | ++ |
| SCC9 | ++ | + | ||
| MDA‐MB‐231 | +++ | ++ | + | |
The symbols +++, ++, and + respectively indicate high−, intermediate−, or low involvement of the respective pathway. Parentheses identify the inhibitor of the pathway which provides evidence for the indicated outcome.