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Generation of diverse GR isoforms by alternative splicing and translation initiation sites. Multiple GR isoforms with distinct signaling properties are generated from a single GR primary transcript. Five splice variants (GRα, GRβ, GRγ, GR-A, and GR-P) with 8 potential translational isoforms (A, B, C1, C2, C3, D1, D2, and D3) for each splice variant have been identified.
