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. 2015 Aug 26;17(1):229. doi: 10.1186/s13075-015-0736-9

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© Aletaha et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Disease activity at baseline of clinical trials stratified by the presence or absence of rheumatoid factor (RF) or anti-citrullinated peptide antibodies (ACPAs). a Rituximab database (IMAGE trial of early RA). b Golimumab database (several trials on RA patients with various disease durations). Please see Table 2 for details on numbers and statistics. CDAI clinical disease activity index, DAS28-ESR Disease Activity Score using 28 joint counts-erythrocyte sedimentation rate, RA rheumatoid arthritis, SDAI simplified disease activity index