Table 3.
Chr. | Position | Gene | Variant | Minor Allele | A/A | A/B | B/B | MAF | Domain | ORaallele (95 % CI) | P value |
---|---|---|---|---|---|---|---|---|---|---|---|
11 | 11:113412737 | DRD2 | rs6277 | T | 80 | 118 | 60 | 0.23 | Cognitive flexibility | 1.6 (1.2–2.6) | 0.004 |
11 | 11:113412737 | DRD2 | rs6277 | T | 80 | 118 | 60 | 0.23 | Executive function | 3.3 (2.0–5.7) | 0.001 |
11 | 11:113400106 | ANKK1 | rs1800497 | T | 102 | 117 | 40 | 0.16 | Cognitive flexibility | 1.1 (0.7–1.8) | 0.71 |
ORs adjusted for self-reported ethnicity/race, alcohol use severity, viral load, CD4 count, cannabis and cocaine use
MAF minor allele frequency
aOR per allele (ORallele) for the additive model