Table 1.
Variable | Control | Lowa | Mediuma | Higha |
---|---|---|---|---|
n | 191 | 186 | 246 | 261 |
% Male | 35.60 | 32.26 | 33.33 | 43.68 |
% Caucasian | 100.00 | 96.79 | 97.01 | 97.20 |
Age | 43.11 (11.32) | 35.20 (7.45) | 40.90 (9.51) | 44.09 (9.87) |
Education (years) | 14.70 (2.69) | 14.53 (2.53) | 14.54 (2.65) | 14.22 (2.71) |
CAG repeat length | 20.08 (3.53) | 40.82 (1.54) | 42.21 (2.06) | 43.74 (2.73) |
UHDRS scoreb | 2.34 (2.90) | 3.06 (3.42) | 4.11 (4.19) | 6.67 (6.03) |
Confidence in motor diagnosis | 0.35 (0.55) | 0.59 (0.67) | 0.72 (0.75) | 1.09 (0.94) |
Note. CAG = cytosine-adenine-guanine; UHDRS = Unified Huntington’s Disease Rating Scale.
Classification of participants into Low, Medium, and High is based on the CAG-age product (CAP) (see “Method” section). Low: low probability (> 15 years from diagnosis); Medium: medium probability (9–15 years from diagnosis); High: high probability of near-future diagnosis (estimated to be <9 years from diagnosis).
The UHDRS assesses motor functioning. Scores range from 0 to 124, with higher scores reflecting more impairment.