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. Author manuscript; available in PMC: 2015 Aug 26.
Published in final edited form as: Mol Microbiol. 2013 Apr 12;88(3):603–618. doi: 10.1111/mmi.12214

Fig. 6.

Fig. 6

Di-galactoside expression protects against binding and bactericidal activity of the anti-LPS mAb 6E4. Bactericidal assays for the serial passage of R2846 lic1D– in mAb 6E4 and baby rabbit serum (BRS), with the round of exposure indicated (A, 15% BRS and mAb 6E4; representative experiment in triplicate). Bactericidal assays in mAb 6E4 and BRS for lic2A and lgtC phase-on variants and mutants (B, 15% BRS and mAb 6E4). Histogram and graphical summary for binding of mAb 6E4 to lic2A and lgtC phase-on variants (black), a lic2A phase-on, lgtC– mutant (dark grey) and a lic2A– mutant (light grey) in R2846 lic1D–(C). Data shown are means and SEM. Statistical analysis (n ≥ 3) was performed by an unpaired t-test; *P < 0.05, **P < 0.01, ***P < 0.001.