Table 2.
Discontinuation and clinical events.
| Discontinuation | Group A infrequent measurement (n=240) | Group B frequent measurement (n=140) | p (χ2 test) |
|---|---|---|---|
| Total no. discontinued | 98 (41%) | 39 (28%) | 0.01⁎ |
| For short-term use | 58 (24%) | 18 (13%) | <0.01⁎ |
| Other reasons for discontinuation | 40 (17%) | 21 (15%) | 0.77 |
| Prolonged aPTT | 3 (1%) | 4 (3%) | 0.26 |
| Gastrointestinal disorders | 10 (4%) | 3 (2%) | 0.38 |
| Minor bleeding | 2 (0.8%) | 3 (2%) | 0.36 |
| Others | 25 (10%) | 11 (8%) | 0.47 |
| Clinical events | |||
| Stroke or systemic embolism | 1 (0.4%) | 0 (0%) | 1.000 |
| Hemorrhagic events | |||
| Any bleeding | 11 (5%) | 4 (3%) | 0.58 |
| Bleeding requiring hospitalization | 0 | 0 | |
| Minor bleeding | 11 (5%) | 4 (3%) | 0.41 |
| Discontinued/continued | 2/11 | 3/4 | |
Statistically significant (p<0.05).