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. 2015 Sep;21(9):1520–1528. doi: 10.3201/eid2109.141333

Table 1. Key uses and findings of Active Bacterial Core surveillance data for vaccine development, evaluation, and policy formulation*.

Pathogen Vaccines Key uses and findings
Streptococcus pneumoniae
PCV7 and PCV13
Selection of serotypes included in PCV7and PCV13
Informed ACIP recommendations for children <5 y of age
Tracking postlicensure declines in cases
Documented effectiveness of PCV7
Monitoring incidence of nonvaccine serotypes
Accelerated regulatory approval of PCV13
Informed ACIP recommendations for PCV13 use in immunocompromised adults and children
Neisseria meningitidis
Conjugate vaccines, serogroup B vaccines
Informed ACIP recommendations for children 11–18 y of age
Informed ACIP recommendations for booster dose
Documented vaccine effectiveness
Informed ACIP infant meningococcal recommendations
Evaluated potential effect on serogroup B disease in United States
Haemophilus influenzae
Hib vaccine
Tracking postlicensure declines in Hib disease
Tracking shift toward non-Hib disease;
Evaluated effect of vaccine shortages
Group A Streptococcus
M-type vaccine
(under development)
Estimated degrees of protection against severe group A streptococcal infections
Group B Streptococcus
Trivalent vaccine
(under development)
Informing development of vaccine to prevent early-onset (within 1 week of life) group B streptococcal disease
Methicillin-resistant Staphylococcus aureus S. aureus vaccine
(under development) Determining population groups to target

*ACIP, Advisory Committee on Immunization Practices; Hib, H. influenzae type b vaccine; PCV7, 7-valent pneumococcal conjugate vaccine; PCV13, 13-valent pneumococcal conjugate vaccine. An expanded version of this table with references is available in the online Technical Appendix (http://wwwnc.cdc.gov/EID/article/21/9/14-1333-Techapp1.pdf).