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. 2015 Aug 26;11(8):e1004474. doi: 10.1371/journal.pcbi.1004474

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© 2015 Balagam, Igoshin

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — (A) Snapshot of the simulation with periodically reversing agents (η = 0.24) at 180 min of simulation time. Reversing agents did not show significant clustering. (B) Mean cluster sizes, 〈m〉, in simulation as a function of cell density, η, for agents following slime trails (green line) and agents without slime trails (black line). Agents following slime trails showed a significant increase in mean cluster size compared to agents without slime-trail-following. (C) Snapshot of the simulation for periodically reversing cells with the slime-trail-following mechanism (η = 0.24, L _s = 11 μm, ε _s = 1.0, refer to Methods for details) at 180 min of simulation time. Agents show improved clustering compared to those without the slime-trail-following mechanism. (D) Orientation correlation 〈cos 2Δθ _r〉 among agents for reversing cells (black) and reversing cells with the slime-trail-following mechanism (green). Dashed and solid lines are orientation correlation values at 1 min and 180 min of simulation time, respectively. Orientation correlation with neighbors improved for larger neighbor distances with the slime-trail-following mechanism.