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. 2015 Aug 26;10(8):e0135655. doi: 10.1371/journal.pone.0135655

Fig 4. Conserved sequence evolution of ChvI in Rhizobiales and selected Rhodobacterales.

Fig 4

As a cognate TCS pair, ChvI and ExoS sequences are expected to diversify at similar rates. However, the ChvI phylogeny suggests that it is under strong purifying selection with the lowest amino-acid substitution rate among the three components. It is possible that the functional role of ChvI orthologs (i.e., DNA binding) limits diversification.