Table 1. Ability of decitabine-treated wound epithelia to participate in blastema formation.
Treatment | Total | 1° Blastema | No Blastema | 2° Blastema |
---|---|---|---|---|
Decitabine | 6 | 4 (67%) | 2 (33%)* | 0 (0%) |
2’-deoxycytidine (control) | 8 | 1** (12%) | 5 (63%) | 2 (25%) |
* The presence of a decitabine bead could not be confirmed 24 hour after grafting in two additional wounds that did not form an ectopic blastema (a total of 8 limbs were grafted), and those data were not included.
** A tear in the WE/AEC of this wound that re-healed and formed a new WE/AEC was observed 24 hours after grafting.