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Alcohol consumption is associated with the induction of retinoic acid-catabolizing CYPs. A) Consumption of 6.4% alcohol for 2 wk was associated with increased mRNA expression levels of Cyp26a1 and Cyp26b1 in the liver (n = 8–11; reference gene, 18s). B) Consumption of 6.4% alcohol for 2 wk was also associated with increased protein expression levels of CYP2E1 and CYP26A1, but not CYP26B. *P < 0.05 vs. control; Student’s t test.
