Table 1. Clinical and metabolic characteristics of the study participants in the total group and according to HOMA-IR.
| Total group n = 303 | HOMA-IR ≤ 2.5 n = 185 | HOMA-IR >2.5 n = 89 | P-value | |
|---|---|---|---|---|
| Age (years) | 51.5±13.3 | 50.3±13.4 | 52.7±11.6 | 0.136 |
| Men, n (%) | 104 (34.3%) | 56 (30.3%) | 41 (46.1%) | 0.012 |
| BMI (kg/m2) | 27.4±5.2 | 25.7±4.3 | 31.5±4.8 | < 0.0001 |
| SBP (mmHg) | 125±16 | 122±17 | 133±13 | < 0.0001 |
| DBP (mmHg) | 78±10 | 77±10 | 83±10 | < 0.0001 |
| c-f PWV (m/s) | 11.96±2.61 | 10.46±2.34 | 12.01±2.93 | < 0.0001 |
| FG (mmol/l) | 5.8±1.4 | 5.3±0.8 | 6.8±1.9 | < 0.0001 |
| 2hOGTT(mmol/l) | 5.7±1.8 | 5.4±1.6 | 6.6±2.2 | 0.0004 |
| HbA1c (mmol/l) | 5.5±1.0 | 5.3±0.7 | 6.1±1.2 | < 0.0001 |
| LTL | 9.76±0.50 | 9.86±0.46 | 9.61±0.47 | < 0.0001 |
| TA | 0.59±0.39 | 0.63±0.38 | 0.55±0.42 | 0.249 |
Abbreviations: BMI: body mass index; c-f PWV: carotid-femoral pulse wave velocity; DBP: diastolic blood pressure; FG: fasting glucose; HbA1c: glycosylated hemoglobin; HOMA-IR: homeostasis model assessment of insulin resistance; LTL: leukocyte telomere length; SBP: systolic blood pressure; TA: telomerase activity; 2h OGTT:2-h glucose level following the oral glucose tolerance test; P-value: p between HOMA-IR ≤ 2.5 and HOMA-IR >2.5 groups