Table 1. Characteristics of healthy individuals and sepsis patients.
| Healthy Individuals (N = 40) | Sepsis Patients (N = 40) | P value* | |
|---|---|---|---|
| Age (years) | 43 (30–55) | 61 (49–76) | <0.001 |
| Males, N (%) | 18 (45) | 24 (60) | 0.18 |
| Cancer, N (%) | - | 1 (2.5) | - |
| Smoking, N (%) | 12 (30) | 8 (20) | 0.44 |
| Severe sepsis, N (%) | - | 23 (58) | - |
| Septic shock, N (%) | - | 17 (42) | - |
| SOFA at admission | - | 7 (4–10) | - |
| DIC (ISTH), N (%) | - | 5 (12.5) | - |
| DIC (JAAM), N (%) | - | 21 (52.5) | - |
| Mortality, N (%) | - | 8 (20) | - |
| Timing between onset of sepsis and sampling (h) | - | 12 (6–24) | - |
| Subjects on heparin, N (%) | - | 1 (2.5%) | - |
| Site of infection | |||
| Pulmonary, N (%) | - | 23 (57.5) | - |
| Abdominal, N (%) | - | 14 (35) | - |
| Soft tissue, N (%) | - | 2 (5) | - |
| Meningitis, N (%) | - | 1 (2.5) | - |
| Microorganism | |||
| Gram-positive cocci | - | 14 (35) | - |
| Enterobacteriae | - | 4 (10) | - |
| Other gram-negative bacilli | - | 4 (10) | - |
| Virus/Pneumocystis carinii | - | 1 (2.5) | - |
| Unknown | - | 17 (42.5) | - |
*From Mann-Whitney (continuous variables) or Fisher’s exact test (categorical variables).
Numbers in table refer to median (25th– 75th) or N(%). Abbreviations: SOFA, Sequential Organ Failure Assessment; DIC, disseminated intravascular coagulation; ISTH, International Society of Thrombosis and Haemostasis; JAAM, Japanese Association for Acute Medicine. Gram-positive microorganisms were: Methicillin Resistant Staphilococcus Aureus, Methicillin Subsceptible Staphilococcus Aureus, Enterococcus, Streptococcus Pyogenes, Streptococcus Pneumoniae. Enterobacteriae were: Escherichia Coli, Enterobacter, Serratia Marcescens. Other gram-negative bacilli were: Acynetobacter, Legionella Pneumophila. Virus was H1N1 influenza A virus.