Table 1. The General Features.
Groups | |||
---|---|---|---|
Factors | WKY | SHR | SHR+Sil100 |
Body Weight (g) | 402 ± 5 | 326 ± 16 † | 336 ± 12 † |
Prostate Weight (mg) | 630 ± 35 | 926 ± 31 † | 863 ± 54 † |
PBR (×10 −3 ) | 1.57 ± 0.09 | 2.86 ± 0.07 † | 2.56 ± 0.11 † # |
Heart Rate (bpm) | 338.0 ± 9.6 | 302.4 ± 3.9 † | 324.0 ± 9.8 |
Mean Blood Pressure (mmHg) | 106.5 ± 1.1 | 166.0 ± 5.9 † | 154.7 ± 4.5 † |
PBR: Prostate body weight ratio (prostate weight/body weight); WKY: 18-week-old WKY rats treated with vehicle, p.o.; SHR: 18-week-old SHRs treated with the vehicle, p.o.; SHR+Sil100: 18-week-old SHRs treated with silodosin at a daily dose of 100 μg/kg, p.o.
Data are shown as mean ± SEM of eight separate determinations in each group.
†: Significantly different from the WKY group (P < 0.05);
#: Significantly different from the SHR group (P < 0.05).