Table 1. Physiological parameters under regular salt diet or sodium-deficient diet.

Parameters	Regular salt diet
	WT	Δ/+	Δ/Δ
n	6	7	5
Body weight (g)	22.70±0.77	22.46±1.59	20.49±1.77
Plasma aldosterone (pg/ml)	358.5±156.8	353.9±126.3	586.6±304.4
Plasma sodium (mmol)	143.15±1.43	145.18±0.66	143.65±0.60
Plasma potassium (mmol)	5.37±0.28	5.32±0.22	5.32±0.11
CAP1, relative mRNA expression (% of control)	100±18.37	97.96±14.78	99.44±17.10
CAP3, relative mRNA expression (% of control)	100±10.16	84.15±6.70	84.80±5.13
Furin, relative mRNA expression (% of control)	n.d.	n.d.	n.d.
	Sodium-deficient diet
	WT	Δ/+	Δ/Δ
n	5	5	4
Body weight (g)	25.75±1.36	25.58±1.48	23.44±2.44
Plasma aldosterone (pg/ml)	803.3±203.6	474.3±157.9	723.7±300.6
Plasma sodium (mmol)	152.20±1.83	155.94±1.97	156.28±3.34
Plasma potassium (mmol)	4.55±0.31	4.79±0.14	4.31±0.29
CAP1, relative mRNA expression (% of control)	100±9.96	119.09±10.06	72.11±4.56
CAP3, relative mRNA expression (% of control)	100±4.72	113.10±10.39	74.93±13.08
Furin, relative mRNA expression (% of control)	100±2.97	123.76±17.44	144.04±8.02

Physiological parameters of CAP2/Tmprss4 wildtype (WT), heterozygous mutant (HET, Δ/+) and knockout (KO, Δ/Δ) mice under regular sodium or sodium-deficient diets. Data are presented as mean ± SEM.