Table 2.

EC₅₀ of selected Mtz-triazoles against G. lamblia strains. The EC₅₀ values for G. lamblia WB strain are shown from Table 3 for comparison.

Compound		EC50 (μM)
		G. lamblia
		WB	106	713	713M
		MtzS	MtzS	MtzS	MtzR
1	metronidazole	7.9	2.8	2.3	17
4a	phenyl	0.25	0.28	0.16	2.3
4b	p-OMe-phenyl	0.27	0.64	0.64	1.0
4c	p-Cl-phenyl	0.20	0.89	1.2	3.5
4d	p,m-Cl2-phenyl	0.39	1.1	2.5	1.2
4e	p-Me-phenyl	0.18	0.29	0.29	1.0
4f	methyl ester	3.0	2.0	1.8	3.1
4h	pyridine	0.74	0.38	0.28	0.95
4k	benzyl	0.70	0.51	0.32	1.1
4l	CHOH-phenyl	4.4	2.2	2.4	3.0
4m	CH2NMe-benzyl	1.6	1.1	0.71	2.2
4n	thiophene	0.37	0.34	0.18	0.9