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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Stroke. 2015 Aug 6;46(9):2562–2567. doi: 10.1161/STROKEAHA.115.009656

Table 2.

Baseline Characteristics for the SAMMPRIS Medical Group vs SAMMPRIS-Eligible WASID Patients*

Characteristic SAMMPRIS Medical Group (n=227) WASID (n=143) p-value

Age (years) 59.5 ± 11.8 62.5 ± 10.0 0.009

Female Gender 82 (36%) 55 (38%) 0.66

Black Race 49 (22%) 37 (26%) 0.38

History of Hypertension 203 (89%) 109 (76%) 0.001

History of Diabetes 97 (43%) 62 (43%) 0.91

Previous or Current Smoker 149 (66%) 101 (71%) 0.36

History of Coronary Artery Disease 59 (26%) 41 (29%) 0.63

History of Ischemic Stroke (not the qualifying event) 58 (26%) 34 (24%) 0.71

Not Using Statin at Enrollment 31 (14%) 56 (39%) < 0.0001

Modified Rankin Grade ≥ 1 159 (70%) 95 (66%) 0.49

NIH Stroke Scale > 1 88 (39%) 50 (35%) 0.51

Physical Activity Out of Target 161 (71%) 105 (73%) 0.64

Old Infarcts in the Territory of the Symptomatic Artery 75/222 (34%) 28/130 (22%) 0.015

Qualifying Event was a Stroke 152 (67%) 90 (63%) 0.43

On Antithrombotic Therapy at Qualifying Event 140 (62%) 75 (52%) 0.084

Time from Qualifying Event to Randomization (days) 7 (4 – 19) 8 (5 – 14) 0.87

Symptomatic Artery < 0.0001
 Internal Carotid Artery 49 (22%) 26 (18%)
 Middle Cerebral Artery 105 (46%) 43 (30%)
 Vertebral Artery 22 (10%) 24 (17%)
 Basilar Artery 51 (22%) 38 (27%)
 Combination 0 12 (8%)

Symptomatic Artery in Posterior Circulation 73 (32%) 74 (52%) 0.0002

Percent Stenosis of Symptomatic Artery § 81 ± 7 78 ± 7 0.0006

Categories of Percent Stenosis of Symptomatic Artery § 0.0004
 70–79% 102 (45%) 94 (66%)
 80–89% 97 (43%) 40 (28%)
 90–99% 28 (12%) 9 (7%)

Systolic BP (mmHg) 146.8 ± 21.8 139.1 ± 17.8 0.0002

Diastolic BP (mmHg) 82.3 ± 12.0 76.5 ± 9.5 < 0.0001

BMI (kg/m2) 30.7 ± 6.3 (n=140) 29.4 ± 5.7 0.048

LDL (mg/dl) (n=226) 97.7 ± 36.6 (n=120) 125.4 ± 39.7 < 0.0001

HDL (mg/dl) (n=226) 38.8 ± 10.1 (n=124) 43.8 ± 13.4 0.0004

HgbA1c (%) (For patients with a history of diabetes) (n=91) 7.6 (6.9 – 10.2) (n=42) 8.0 (6.5 – 10.3) 0.89
*

Values are mean ± standard deviation or number (%) or median (inter-quartile range).

Comparisons of the baseline characteristics of the two studies were made using either an independent groups t-test (for means), Fisher’s exact test (for percentages) or the Wilcoxon rank sum test (for medians).

Physical activity was measured in the two studies as follows: SAMMPRIS used the Physician-based Assessment and Counseling for Exercise (PACE) Current Physical Activity Status Score with a score of 1–3 considered in-target. WASID used four categories (Sedentary, Minimal, Moderate, Vigorous) with Moderate or Vigorous considered in-target. (see on-line supplement for details).

§

Percent stenosis according to the reading of the angiogram by the study physician at the patient’s clinical site.