Table 2.
Comparison of cognitive testing between patients with and without HE within each group. Patients with HE performed worse than those without HE in both Alc and Nalc groups.
Alcoholic cirrhosis | Non-alcoholic cirrhosis | |||
---|---|---|---|---|
No-HE (n=19) | HE (n=27) | No-HE (n=48) | HE (n=44) | |
Number connection-A (sec) | 41 ± 4.4 | 48.9 ± 4.3 | 37 ± 2.1 | 48.0 ± 3.5** |
Number connection-B (sec) | 103.8 ± 12.8 | 153.9 ± 22.8 | 89.7 ± 5.2 | 156.23 ± 17.4** |
Inhibitory Control Lures (number) | 12.9 ± 2.5 | 14.3 ± 1.7 | 11.1 ± 1.3 | 12.6 ± 1.2 |
Digit Symbol (score) | 53.7 ± 4.5** | 40.4 ± 2.7 | 56.6 ± 2.1** | 47.5 ± 2.8 |
Block design (score) | 24.5 ± 3.3 | 19.2 ± 2.2 | 27.5 ±1.9 | 24.4 ± 2.0 |
Line tracing time (sec) | 120.5 ± 15.6 | 120.7 ± 10.6 | 112.5 ± 8.0 | 124.9 ± 10.4 |
Line tracing errors (number) | 33.1 ± 7.1 | 47.8 ± 6.5 | 28.7 ± 4.3 | 36.3 ± 5.0 |
Serial Dotting (sec) | 71.5 ± 5.3 | 100.1 ± 9.7* | 65.8 ± 4.3 | 77.4 ± 4.7* |
Inhibitory Control Targets (%) | 95.5 ± 2.2* | 85.8 ± 3.0 | 97.1 ± 0.6** | 92.6 ± 1.1 |
p<0.05
p<0.005 no-HE vs. HE (within each group); data is presented as Mean±SEM; a high score on block design, digit symbol and inhibitory control targets and a low score on the rest indicate poor cognition.
HE: prior overt hepatic encephalopathy, No-HE: no history of overt hepatic encephalopathy