Table 3.
Cross-sectional MRS
| Right Parietal White Matter | Posterior Gray Matter | Anterior Cingulate Cortex | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Cho | Glx | mI | Cho | Glx | mI | Cho | Glx | mI | |
| All | |||||||||
| Alc (n=46) | 0.256 | 2.788* | 0.302 | 0.192 | 2.784 | 0.348 | 0.245 | 3.314* | 0.425 |
| Nalc (n=102) | 0.266 | 2.439 | 0.465* | 0.186 | 2.617 | 0.493* | 0.253 | 2.925 | 0.526* |
| No-HE | |||||||||
| Alc (n=13) | 0.261 | 2.587* | 0.513 | 0.180 | 2.760* | 0.432 | 0.249 | 3.128* | 0.522 |
| Nalc (n=46) | 0.287 | 2.040 | 0.644‡‡ | 0.190 | 2.268 | 0.621*‡‡ | 0.262 | 2.525 | 0.635‡‡ |
| HE | |||||||||
| Alc (n=27) | 0.254 | 2.911‡‡ | 0.229 | 0.196 | 2.773 | 0.336 | 0.241 | 3.299 | 0.386 |
| Nalc (n=44) | 0.240‡‡ | 2.791‡‡ | 0.296 | 0.186 | 2.953‡‡ | 0.389 | 0.245 | 3.355‡‡ | 0.417 |
*
p<0.05 Alc vs. Nalc ;
‡‡
p<0.005 no-HE vs. HE (for Alc & Nalc separately).
Alcoholic cirrhosis group (Alc) had higher Glx and lower mI than non-alcoholic cirrhosis group (Nalc). This difference disappeared with the presence of HE. Furthermore, results show that HE influence is predominant in Nalc but not in Alc.