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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Spine J. 2015 Apr 23;15(9):2045–2054. doi: 10.1016/j.spinee.2015.04.026

Figure 3. Collagen hollow spheres release the greatest amount of infliximab over time.

Figure 3

(A) Cumulative infliximab concentration in Fibrin alone showed large amounts of drug released but Fibrin degraded completely within 6 days indicating is is not capable of long-term release. (B) Cumulative infliximab concentration over 20 days showed increased drug release from CHS alone loaded with 320 μg infliximab, steady release at low levels from FibGen alone directly mixed with 320 μg infliximab, and impeded drug release in FibGen+CHS loaded with 320 μg infliximab.