Table 4. Equilibrium values.
Variable | Unit | Description | Reference | ||
---|---|---|---|---|---|
ωi = 1400 | μm | cell volume | Matsui et al. (2000) | ||
Hi = 28.7 | μm | cell height | Matsui et al. 2000 | ||
[Na+]p = 103 | mM | PCL Na+ concentration | Jayaraman, Song et al. (2001) | ||
[K+]p = 20.8 | mM | PCL K+ concentration | Namkung et al. (2009) | ||
[Cl−]p = 92 | mM | PCL Cl− concentration | Jayaraman, Song et al. (2001) | ||
[H+]p = 1.55×10−4 | mM | PCL H+ concentration | Jayaraman, Joo et al. (2001) | ||
|
mM |
|
determined from modelb | ||
[CO2]p = 11.6 | mM | PCL CO2 concentration | determined from Eq. (25) | ||
[Na+]i = 22 | mM | intracellular Na+ concentration | Willumsen & Boucher (1991) | ||
[K+]i = 117 | mM | intracellular K+ concentration | Treharne et al. (2006) | ||
[Cl−]i = 42.7 | mM | intracellular Cl− concentration | Willumsen et al. (1989) | ||
[H+]i = 1.23×10−4 | mM | intracellular H+ concentration | Stewart et al. (2001) | ||
|
mM |
|
Smith & Crampin (2006) | ||
[CO2]i = 3.5 | mM | intracellular CO2 concentration | determined from Eq. (26) | ||
Va = -29 | mV | apical membrane potential | Cotten et al. (1987) | ||
Vb = -36.2 | mV | basolateral membrane potential | Willumsen et al. (1989) | ||
U0 = 1.92 | μm/s | submucosal gland secretory flux | determined from model |
The equilibrium PCL concentration was found using the electroneutrality condition: