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. Author manuscript; available in PMC: 2016 Oct 7.
Published in final edited form as: J Theor Biol. 2015 Jul 10;382:198–215. doi: 10.1016/j.jtbi.2015.06.050

Table 4. Equilibrium values.

Variable Unit Description Reference
ωi = 1400 μm cell volume Matsui et al. (2000)
Hi = 28.7 μm cell height Matsui et al. 2000
[Na+]p = 103 mM PCL Na+ concentration Jayaraman, Song et al. (2001)
[K+]p = 20.8 mM PCL K+ concentration Namkung et al. (2009)
[Cl]p = 92 mM PCL Cl concentration Jayaraman, Song et al. (2001)
[H+]p = 1.55×10−4 mM PCL H+ concentration Jayaraman, Joo et al. (2001)
[HCO3]p=31.8
mM
PCL HCO3concentration
determined from modelb
[CO2]p = 11.6 mM PCL CO2 concentration determined from Eq. (25)
[Na+]i = 22 mM intracellular Na+ concentration Willumsen & Boucher (1991)
[K+]i = 117 mM intracellular K+ concentration Treharne et al. (2006)
[Cl]i = 42.7 mM intracellular Cl concentration Willumsen et al. (1989)
[H+]i = 1.23×10−4 mM intracellular H+ concentration Stewart et al. (2001)
[HCO3]i=12
mM
intracellular HCO3concentration
Smith & Crampin (2006)
[CO2]i = 3.5 mM intracellular CO2 concentration determined from Eq. (26)
Va = -29 mV apical membrane potential Cotten et al. (1987)
Vb = -36.2 mV basolateral membrane potential Willumsen et al. (1989)
U0 = 1.92 μm/s submucosal gland secretory flux determined from model
b

The equilibrium PCL HCO3 concentration was found using the electroneutrality condition:

[HCO3]p=[Na+]p+[K+]p[Cl]p[H+]p,=31.8mM.