Table 2.
Characteristics of study subjects in 1998/99 as a function of outcome
| Normal | MCI | AD | Effect size1 | |
|---|---|---|---|---|
| n | 83 | 55 | 151 | |
| Age | 78.7 (3.9) | 78.7 (3.4) | 79.7 (3.5) | 0.02 |
| Education2 | 68.7 (57) | 67.2 (39) | 59.6 (90) | 0.09 |
| Sex2 | 44.6 (37) | 63.8 (37) | 68.2 (103) | 0.21* |
| Race2 | 85.5 (71) | 79.3 (46) | 83.4 (126) | 0.06 |
| APOE ε42 | 23.1 (18) | 21.8 (12) | 27.0 (38) | 0.05 |
| Estimated IQ | 119.9 (8.3) | 120.3 (7.9) | 117.3 (9.0) | 0.03 |
| 3MSE3 | 96.6 (3.8) | 97.0 (3.6) | 95.8 (4.2) | 0.02 |
| DSST4 | 48.9 (11.5) | 50.6 (13.3) | 44.6 (12.0) | 0.04* |
| CES-D5 | 4.09 (3.6) | 4.01 (3.8) | 5.00 (4.2) | 0.01 |
| Hypertension2 | 45.8 (38) | 44.8 (26) | 49.0 (74) | 0.04 |
| Diabetes2 | 9.6 (8) | 12.1 (7) | 16.6 (25) | 0.09 |
| White matter hyperintensities2 | 32.5 (27) | 32.8 (19) | 37.1 (56) | 0.05 |
| MRI-identified infarcts2 | 25.3 (21) | 22.4 (13) | 27.8 (42) | 0.05 |
| Whole brain grey matter6 | 37.2 (1.1) | 37.4 (1.3) | 37.3 (1.2) | 0.01 |
1)
Cohen’s f for continuous data, Cramer’s V for categorical data.
2)
Percent (n) Present, Yes, Female, Caucasian, Greater than High School.
3)
Modified Mini Mental Status Examination [10].
4)
Digit symbol substitution test [39].
5)
Center for Epidemiological Studies–Depression scale [76].
6)
As a percentage of total intracranial volume.
*
p<0.05.