Table 4.
Judged response to fluid challenge
| Response classification [no. (%) of 2162] | |
| Negative response | 429 (19.8 [18.1–21.5]) |
| Positive response | 1544 (71.4 [69.5–71.4]) |
| Uncertain | 189 (8.7 [7.5–9.9]) |
| Variable use to evaluate response [no. (%) of 1544 with positive response] | |
| Increase in BP | 1039 (67.3 [65.0–69.7]) |
| Decrease vasopressors | 56 (3.6 [2.7–4.5]) |
| Increase in CO | 174 (11.3 [9.7–12.9]) |
| Increase in SV | 100 (6.5 [5.3–7.7]) |
| Decrease in HR | 374 (24.2 [22.1–26.3]) |
| Urine output | 590 (38.2 [35.8–40.6]) |
| Lactate | 281 (18.2 [16.3–20.1]) |
| Skin perfusion | 128 (8.3 [6.9–9.7]) |
| Mental state | 40 (2.6 [1.8–3.4]) |
| ScvO2/SvO2 | 77 (5.0 [3.9–6.1]) |
| SVV/PPV | 110 (7.1 [5.8–8.4]) |
| CVP/PAOP | 256 (16.6 [14.7–18.5]) |
| Other | 132 (8.5 [7.1–9.9]) |
| Safety limit used [no. (%) of 2213] | 577 (27.9 [25.7–30.1]) |
| Variable used in the safety limit group [no. (%) of 577] | |
| CVP | 329 (57.0 [53.0–61.0]) |
| PAOP | 39 (6.7 [4.7–8.8]) |
| GEDVI | 11 (1.9 [4.7–8.8]) |
| EVLWI | 28 (4.9 [3.1–6.7]) |
| SpO2/SaO2 | 105 (18.2 [15.1–21.35]) |
| CO | 8 (1.4 [0.4–2.4]) |
| SVV/PPV | 80 (13.9 [11.1–16.7]) |
| Other | 120 (20.8 [17.5–24.1]) |
BP blood pressure, CO cardiac output, SV stroke volume, HR heart rate, SvO 2 mixed venous oxygen saturation, ScvO 2 central venous oxygen saturation, SVV stroke volume variation, PPV pulse pressure variation, CVP central venous pressure, PAOP pulmonary artery occlusion pressure, GEDVI global end diastolic volume, EVLWI extravascular lung water index