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. 2015 Feb 26;361(3):733–744. doi: 10.1007/s00441-015-2133-8

Table 1.

Effect of phenylthiourea (PTU) on melanosome genesis in wild type melanophores

Treatment Stage I + IIa / total Stage IIIa / total Stage IVa / total
Controlb 0 % 0 % 100 %
PTUc 28.1 %* 69.8 %* 2.1 %*

*P < 0.001 (χ 2 test)

aPercentage of melanosomes at each stage among total melanosomes. Stage I and II melanosomes, partially melanized stage III melanosomes, and fully melanized stage IV melanosomes were according to the mammalian nomenclature of developing melanosomes (Raposo and Marks 2007)

b721 melanosomes were counted in 6 different photographs of melanophores in the 18-day wild type regenerating tails in the absence of PTU (see Fig. 3a)

c815 melanosomes were counted in 5 different photographs of melanophores in the 18-day wild type regenerating tails in the presence of PTU (see Fig. 3b)