Table 2.
Sp. | RFP | INH | EMB | SM | AM | KN | CPM | TOB | OF | CIP | LEV | SPA | MXF | LNZ | CLO | SMZ |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
M. abscessus | 64 | >256 | 32 | 16 | 1 | 2 | 0.5 | 8 | 4 | 2 | 1 | 2 | 1 | 4 | 0.06 | 32 |
M. chelonae | >256 | >256 | 128 | 32 | 4 | 16 | 16 | 2 | 32 | 4 | 16 | 16 | 4 | 8 | 0.25 | 64 |
M. fortuitum | 128 | 64 | 256 | 32 | 0.25 | 4 | <0.03 | 16 | 0.13 | 0.03 | 0.03 | <0.03 | <0.03 | 8 | 0.03 | 2 |
M. septicum | 16 | 256 | 4 | 16 | 0.13 | 0.5 | <0.03 | 1 | 0.25 | 0.06 | 0.13 | 0.03 | 0.06 | 1 | 0.13 | 1 |
M. neoaurum | 1 | >256 | 8 | 0.5 | 0.5 | 0.06 | <0.03 | 0.25 | 0.06 | 0.06 | 0.03 | <0.03 | <0.03 | 0.5 | 0.03 | 0.5 |
| ||||||||||||||||
Sp. | MIN | DOX | TIG | CLR | AZM | ROX | AMC | FOX | CMZ | MEM | RFT | RFB | DAP | THI | PASI | |
| ||||||||||||||||
M. abscessus | 8 | 32 | 4 | <0.03 | <0.03 | 0.03 | >256 | 32 | 32 | 64 | 0.13 | 32 | 64 | 16 | 32 | |
M. chelonae | 64 | >32 | 1 | 0.06 | 0.5 | 2 | >256 | 128 | <0.25 | >256 | 0.13 | 32 | 32 | >256 | >256 | |
M. fortuitum | 8 | 0.03 | 0.5 | 1 | 2 | 4 | >256 | 32 | 4 | 4 | 1 | 16 | 8 | 256 | 2 | |
M. septicum | 32 | 8 | 1 | 1 | 16 | 4 | >256 | 128 | 1 | 16 | 0.13 | <0.03 | 32 | 256 | 4 | |
M. neoaurum | 0.03 | 0.06 | 0.03 | 1 | 1 | 2 | 32 | 8 | 1 | 0.5 | 0.06 | 0.13 | 4 | >256 | 64 |
Note 1: M. abscessus: ATCC19977; M. chelonae: ATCC35752; M. fortuitum: DSM44220; M. neoaurum: ATCC25795; and M. septicum: DSM44393.
Note 2: INH: isoniazid; RFP: rifampicin; EMB: ethambutol; SM: streptomycin; AM: amikacin; KN: kanamycin; CPM: capreomycin; TOB: tobramycin; OF: ofloxacin; CIP: ciprofloxacin; LEV: levofloxacin; SPA: sparfloxacin; MXF: moxifloxacin; LNZ: linezolid; CLO: clofazimine; SMZ: sulfamethoxazole; CLR: clarithromycin; AZM: azithromycin; ROX: roxithromycin; MIN: minocycline; DOX: doxycycline; TIG: tigecycline; AMC: Amoxicillin-clavulanic Acid; FOX: cefoxitin; CMZ: cefmetazole; MEM: meropenem; RPT: rifapentine; RBT: rifabutin; DAP: dapsone; THI: thioacetazone; PASI: pasiniazid.
Note 3: Bold, italic values indicate drug susceptibility. Values shown in bold indicate moderate drug susceptibility.