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. 2015 Aug 27;6:242. doi: 10.3389/fphys.2015.00242

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Copyright © 2015 McConnell, Singh, Fan, Hernandez, Portillo, Reiser and Tikunova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of the D73N mutation on electrocardiographic parameters. (A) Representative ECG tracings from 8 ± 0.4 week old WT and D73N (+/−) mice. (B) Comparison of QRS intervals between 4 ± 0.1, 8 ± 0.4, and 12 ± 0.4 week old WT and D73N (+/−) mice. Data represent mean ± S.E. for at least 11 mice per group. (C) Comparison of QT intervals between 4 ± 0.1, 8 ± 0.4, and 12 ± 0.4 week old WT and D73N (+/−) mice. Data represent mean ± S.E. for at least 11 mice per group. ^*D73N (+/−) values significantly different from their respective WT values (p < 0.05).