Table 3.

Regions showing functional connectivity differences of the left/right fusiform gyrus between the aMCI and control group (P < 0.01, 28 voxels, corrected for multiple comparisons).

Brain regions	BA	Cluster size	MNI			Max T2	CG	aMCI
			x	y	z		T1	T1
FUNCTIONAL CONNECTIVITY OF THE LEFT FUSIFORM GYRUS
aMCI < CG
R.FG (+)	37	61	33	−75	−15	−3.8803	7.891	3.195	↓+
aMCI > CG
L.MOG (+)	19	134	−27	−90	24	3.6043	1.606	6.852	↑+
L.LING (+)	19	93	−29	−61	2	3.8262	2.581	5.697	↑+
L.PreCU (−)	7	41	−9	−60	39	3.1048	−4.353	−0.391	↑−
R.ACC (−)	33	22	6	21	18	3.6612	−2.675	−1.28	↑−
R.THAL (+)	–	56	−8	−16	17	3.6910	2.364	5.031	↑+
aMCI < CG	BA	Cluster size	x	y	z	Max T2	T1	T1
FUNCTIONAL CONNECTIVITY OF THE RIGHT FUSIFORM GYRUS
L.ITG (+)	37	65	−48	−42	−18	−3.6456	6.439	1.166	↓+
L.FG (+)	37	42	23	−51	−13	−3.2262	9.954	8.258	↓+
L.LING (+)	17	74	3	−73	6	−4.1071	5.804	2.717	↓+
L.ParaHip (+)	34	28	−12	−6	−24	−4.0105	3.121	0.336	↓+
aMCI > CG
R.SMG (+)	2	42	65	−22	29	3.858	1.684	4.325	↑+
L.SMA (+)	32	51	−5	11	47	4.03	1.923	6.471	↑+
L.MOG (+)	19	94	−39	−84	30	2.9629	3.955	5.336	↑+
R.ACC (−)	24	33	9	30	9	4.5676	−3.588	−0.506	↑−

CG, control group; FG, fusiform gyrus; MOG, middle occipital gyrus; LING, lingual gyrus; PreCU, precuneus; ACC, anterior cingulate cortex; THAL, thalamus; ITG, inferior temporal gyrus; ParaHip, parahippocampus; SMG, supramarginal gyrus; SMA, supplementary motor area; L, left; R, right; BA, Brodmann’s area; x, y, z coordinates of primary peak locations in the space of MNI; “+”: positive functional connectivity; “−”: negative functional connectivity; T2 value was obtained by a two-tailed two-sample t-test. The last three columns reveal the detailed condition of decreased and increased connectivity for the identified regions; T1 value was obtained by a one-sample t-test; “↓+”, decrease in positive functional connectivity; “↑+”, increase in positive connectivity; “↑−”, increase in negative connectivity.