Table 1.
Ref. | IRE placement technique | No. of patients | Age in years | Sex in male/female | Time from diagnosis to treatment in months | Survival time in months | Complications | No. of patients with metastasis | No. of patients who received pre IRE chemo and or radiation | No. of patient who received post IRE chemo and or radiation |
Martin et al[38] | Open 52 (96%) lap 2 (4%) | 54 | Median 61 range 45-80 | 23 male/21 female | Median 5.1 range 1-32 | Local PFS 14, distant PFS 15, and OS 20 | 32 (59%) | 0 (0%) | 49 (90%) | 40 (73%) |
Martin et al[43] | Open 48 (100%) | 48 | Median 61 range 27-81 | 26 male/22 female | 6 range 4-13 | OS 22 and PFS 11 | 18 (38%) | 0 (0%) | 33 (69%) | 31 (65%) |
Paiella et al[39] | Open 10 (100%) | 10 | Median 66 | 5 male/5 female | Mean 9.2 | OS 7.5 | 2 (20%) | 0 (0%) | 10 (100%) | 3 (30%) |
Narayanan et al[40] | Perc CT guided 14 (100%) | 14 | Median 57 range 51-72 | 7 male/7 female | Mean 16.6 range 2.4-49.5 | 70% OS at 6 mo | 2 (14%) | 3 (21%) | 14 (100%) | NP |
Månsson et al[41] | Perc US guided 5 (100%) | 5 | Median 65 range 46-89 | 3 male/2 female | NP | 40% OS at 6 mo | 0 (0%) | 0 (0%) | 5 (100%) | NP |
Bagla et al[44] | Perc US with CT confirm | 1 | 78 | Male | CT | Alive at 6 mo | None | None | No | No |
IRE: Irreversible electroporation; US: Ultrasound; CT: Computed tomography; NP: Nondeterministic polynomial.