Table 1. Activities of natural xanthone derivatives.
| Compound number | Compound name | EC50 (μM) | Inhibition ratio at 20 μM (%) |
|---|---|---|---|
| Control | diflunisal | 6.2 ± 0.23* | 97 ± 1.7 |
| 1 | α-mangostin | 15 ± 0.75 | 61 ± 4.7 |
| 2 | 3-isomangostin | >20 | 32 ± 1.3 |
| 3 | 9-hydroxycalabaxanthone | >20 | 29 ± 1.5 |
| 4 | γ-mangostin | 7 ± 0.6 | 97 ± 1.3 |
| 5 | gartanin | >20 | 30 ± 0.79 |
| 6 | 8-deoxygartanin | ND | ND |
| 7 | garcinone C | 10 ± 0.30 | 83 ± 0.23 |
| 8 | norathyriol | 9.7 ± 0.48 | 79 ± 0.49 |
| 9 | 1,3,7-trihydroxy-2-prenylxanthone | 13 ± 1.1 | 67 ± 2.7 |
| 10 | 3,4,5,6-tetrahydroxyxanthone | >20 | 25 ± 0.97 |
| 11 | 1,6,7-trihydroxyxanthone | 14 ± 0.51 | 64 ± 1.2 |
| 12 | Mangiferin | >20 | 8.5 ± 2.1 |
*The EC50 value was calculated using the fluorescence intensity at 0–40 μM concentration.