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. 2015 Feb 20;308(9):H1078–H1085. doi: 10.1152/ajpheart.00679.2014

Fig. 2.

Fig. 2.

In vitro analysis of effects of peroxisome proliferator-activated receptor δ (PPARδ) stimulation. A: reduced fatty acid oxidation rates in response to TNFα stimulation is corrected by PPARδ agonist (GW501516) coincubation but not in response to PPARα agonism (WY14643). B: expression of carnitine palmitoyltransferase-1 (CPT1) decreases under TNFα treatment and increases with coincubation using the PPARδ agonist (C2C12 skeletal muscle myotubes, n = 3 independent experiments per condition. *P < 0.05, **P < 0.01, ***P < 0.001).