Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Feb 27;308(9):H1086–H1095. doi: 10.1152/ajpheart.00501.2014

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 the American Physiological Society

PMC Copyright notice

Fig. 4. — Q510E-SHP2 expression increases force and power generation in skinned cardiac myofibers. A–D: force clamps (for 150–250 ms) and length traces during maximal Ca²⁺ activation of a cardiomyocyte from NTG and TG mice, respectively. E and F: force-velocity and power-load curves of a myocyte (at maximal Ca²⁺ activation) from a NTG mouse heart (open circles) and a TG heart (closed circles). G: force redevelopment traces after a slack-restretch maneuver of a NTG cardiomyocyte (shaded trace) and a TG cardiomyocyte (solid trace) during maximal Ca²⁺ activation. TG cardiomyocyte preparations exhibited faster force redevelopment kinetics than compared with NTG cardiomyocyte preparations. k_tr, rate constant of force development H–K: bar plots summarizing rate constants, tension, and power (both absolute and normalized for cardiomyocyte size) generated by cardiomyocyte preparations from NTG and TG hearts. In all bar graphs, n = 9. *P < 0.05 vs. NTG cardiomyocyte preparations.