Fig. 1.

Inhalational exposure to DCB230 does not affect infarct size. A: representative cardiac section from a vehicle-exposed myocardial ischemia/reperfusion injury 1-day (MI/R 1d) rat showing how the area at risk (AAR) for MI/R injury and area of necrosis (AON) were determined. B: the AAR was consistent between all groups receiving MI/R injury. Additionally, no significant difference in AON was measured between exposure groups at either MI/R 1d or MI/R 7-day (7d) time periods. In this and all figures, n = 10/group except the MI/R 7d vehicle group where n = 9. LV, left ventricle.