Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Symptom improvement
Systematic review	64 men with NIH category IIIA chronic pelvic pain syndrome Data from 1 RCT	Mean changes in NIH-CPSI total score timeframe not reported 23.3 with celecoxib 24.7 with placebo	MD –1.40 95% CI –0.62 to –2.18	Effect size not calculated	celecoxib
Systematic review	64 men with NIH category IIIA chronic pelvic pain syndrome Data from 1 RCT	Mean changes in NIH-CPSI pain domain score timeframe not reported 10.1 with celecoxib 11.1 with placebo	MD –1.00 95% CI –2.27 to +0.27		Not significant
Systematic review	64 men with NIH category IIIA chronic pelvic pain syndrome Data from 1 RCT	Mean changes in NIH-CPSI voiding domain score timeframe not reported 4.9 with celecoxib 4.8 with placebo	MD +0.10 95% CI –0.54 to +0.74		Not significant