Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Quality of life
RCT	100 men In review	Mean score improvement in the NIH-CPSI score for life quality domain 16 weeks 2.0 with pentosan polysulfate 1.0 with placebo	P = 0.031 One review reported a further analysis of NIH-CPSI QoL score from this RCT, which found no significant difference between groups (100 men, timescale not reported: mean changes, 6.9 with pentosan polysulfate v 7.5 with placebo, mean difference –0.60, 95% CI –1.50 to +0.30)	Effect size not calculated	pentosan polysulfate