Table 2.

General characteristics, body composition, muscle function, habitual dietary intake and laboratory values of the healthy control and NSCLC groups

	Healthy controls (n = 11)	NSCLC (n = 13)	Statistical values, P
Gender (m/f)	11/0	13/0
Age (years)	65.8 ± 1.6	68.5 ± 2.1	NS
Weight (kg)	86.2 ± 3.1	79.6 ± 3.7	NS
Body mass index (kg/m2)	27.8 ± 1.1	26.5 ± 1.1	NS
Body composition
Fat-free mass index (kg/m2)	18.9 ± 0.6	18.0 ± 0.7	NS
Fat mass index (kg/m2)	8.0 ± 0.6	7.8 ± 0.6	NS
Whole-body fat-free mass (kg)	59.2 ± 1.9	54.0 ± 2.4	NS
Arms fat-free mass (kg)	6.7 ± 0.3	6.5 ± 0.3	NS
Legs fat-free mass (kg)	19.4 ± 0.8	16.8 ± 0.8	0.02*
Muscle function
Maximal inspiratory pressure (cmH2O)	85.2 ± 10.8	73.3 ± 8.1	NS
Maximal expiratory pressure (cmH2O)	110.7 ± 8.3	98.2 ± 7.7	NS
Handgrip strength
N	260.3 ± 19.3	267.5 ± 9.7	NS
N/FFM	4.4 ± 0.3	5.1 ± 0.3	NS
Handgrip endurance (%)	82.8 ± 5.8	72.6 ± 3.1	0.07
Habitual dietary intake
Energy
kcal	2139 ± 167	1944 ± 215	NS
kcal/kg bw	24 ± 2	25 ± 3	NS
kcal/kg FFM	109 ± 8	110 ± 12	NS
Protein
g	85.5 ± 7.3	70.4 ± 8.4	NS
g/kg bw	1.0 ± 0.1	0.9 ± 0.1	NS
g/kg FFM	4.4 ± 0.4	4.0 ± 0.5	NS
energy%	16.3 ± 1.2	14.6 ± 0.8	NS
Fat (energy%)	35.0 ± 1.7	36.8 ± 1.9	NS
Carbohydrates (energy%)	48.8 ± 1.9	48.6 ± 1.9	NS
Laboratory data plasma
C-reactive protein (mg/l)	1.5 ± 0.4	9.8 ± 3.7	0.04*
Insulin (µIU/ml)	8.1 ± 1.9	9.4 ± 1.1	NS
Glucose (mmol/l)	5.7 ± 0.4	5.6 ± 0.2	NS
HOMA score (MU)	2.0 ± 0.5	2.4 ± 0.3	NS

All values are means ± SEM. Data were analyzed by unpaired Student's t-test.

Significantly different from the control group. *P < 0.05.

NSCLC, nonsmall-cell lung cancer; bw, body weight; FFM, fat-free mass; HOMA, Homeostasis Model Assessment score (marker of insulin resistance).