TABLE III.
No Variant (N = 328) | FBN1 Variant (N = 15*) | P Value | |
Female patients† | 277 (84%) | 13 (87%) | 1 |
Spinal curve‡ | 55° ± 16° | 72° ± 20° | 1.1 × 10−4 |
Height percentile‡ | 46 ± 30§ | 60 ± 32 | 0.15 |
Weight percentile‡ | 57 ± 31§ | 56 ± 32 | 1 |
First-degree relative with treated adolescent idiopathic scoliosis† | 44 (13%) | 2 (13%) | 1 |
Ghent systemic features score‡ (points) | 2.6 ± 1.7# | 4.0 ± 2.2** | 5.3 × 10−3 |
Beighton joint hypermobility score‡ (points) | 1.5 ± 1.7†† | 2.5 ± 2.4** | 0.05 |
One patient had two mutations.
The values are given as the number of patients, with the percentage in parentheses.
The values are given as the mean and the standard deviation.
The values are based on 217 patients.
The values are based on 205 patients.
The values are based on twelve patients.
The values are based on 204 patients.