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. 2015 Aug 7;81(17):5907–5916. doi: 10.1128/AEM.01095-15

FIG 6.

FIG 6

Genome sequence-derived metabolic reconstruction of Pyrobaculum yellowstonensis strain WP30. HK, ATP-dependent hexokinase; PGI, phosphoglucose isomerase; PFK, ATP-dependent phosphofructokinase; FBA, fructose-bisphosphate aldolase/phosphatase; TIM, triosephosphate isomerase; GAPOR, glyceraldehyde-3-phosphate ferredoxin oxidoreductase; GAPN, nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase [phosphoglycerate kinase (PGK) and NAD(P)-dependent phosphorylating GAP dehydrogenase are also present but are not shown]; PGM, phosphoglycerate mutase; GK, glycerate kinase; PYK, pyruvate kinase; PPDK, pyruvate, phosphate dikinase; PWDK, pyruvate-water dikinase; PEPC, phosphoenolpyruvate carboxylase; Fdox, oxidized ferredoxin; Fdred, reduced ferredoxin; LD, lactate dehydrogenase; PFOR, pyruvate:ferredoxin oxidoreductase; ACS, AMP-forming acetyl-CoA synthetase; CDH, citrate synthase; AH, aconitase; IDH, NADP+-dependent isocitrate dehydrogenase; KGOR, 2-oxoglutarate:ferredoxin oxidoreductase; SCS, succinyl-CoA synthetase; SQO, succinate:quinone oxidoreductase; FH, fumarase (class 1); MDH, malic dehydrogenase enzyme; SCR, succinyl-CoA reductase (NADPH); SSR, succinic semialdehyde reductase (NADPH); 4-HCl, 4-hydroxybutyrate-CoA ligase (AMP forming); 4-BUDH, 4-hydroxybutyryl-CoA dehydratase; CCH, crotonyl-CoA hydratase; 3-BUDH, (S)-3-hydroxybutyryl-CoA dehydrogenase (NAD+); ACK, acetoacetyl-CoA β-ketothiolase; HPS, 3-hexulose-6-phosphate synthase; FOR, formaldehyde:ferredoxin oxidoreductase; RPI, ribose-5-phosphate isomerase; PPS, phosphoribosyl pyrophosphate synthase; CoASH, coenzyme A; GD, glutamate dehydrogenase; POR, pyruvate:ferredoxin oxidoreductase; IOR, indolepyruvate:ferredoxin oxidoreductase; VOR, 2-ketoisovalerate:ferredoxin oxidoreductase; KGOR, 2-oxoglutarate:ferredoxin oxidoreductase; AOR, aldehyde:ferredoxin oxidoreductase; FadD, acyl-CoA ligase (acyl-CoA synthetase); FadE, acyl-CoA dehydrogenase; Fad, enoyl-CoA hydratase; Hbd, 3-hydroxyacyl-CoA dehydrogenase; FadA, 3-ketoacyl-CoA thiolase; RMP, ribulose monophosphate pathway.