Table 1.
Validation of studies on association of periodontal disease and cancers
| Cancer site | Number of study | Systematic reviews of RCTs | Randomized controlled trial | Prospective studies | Retrospective studies | Range of the sample sizes in studies | Scientific validation |
|---|---|---|---|---|---|---|---|
| Oral cancer | 10 | 0 | 0 | 4 | 6 | ≥100 | CWD |
| gastric cancer | 5 | 0 | 0 | 2 | 3 | ≥100 | CWD |
| Lung cancer | 3 | 0 | 0 | 1 | 2 | ≥100 | CWD |
| Upper GI and Esophageal Cancer | 7 | 0 | 0 | 2 | 5 | ≥100 | CWD |
| Total cancer | 3 | 0 | 0 | 0 | 3 | ≥100 | CWD |
CWD=Clinically Well Documented, RCTs=Randomized Clinical Trials