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. Author manuscript; available in PMC: 2015 Nov 7.
Published in final edited form as: Oncogene. 2014 Jul 7;34(19):2471–2482. doi: 10.1038/onc.2014.193

Figure 3.

Figure 3

The effect of Cdh1 and Trp53 ablation on proliferation, angiogenesis and steroid hormone receptors. (a) Immunoreactive Ki67 (MKI67) as a marker of cell proliferation, CD31 (PECAM1) as an endothelial cell marker, and steroid hormone receptors (ESR1 and PGR) were detected in the uteri of control and Cdh1d/dTrp53d/d mice at 6 and 12 months of age. (b) Semiquantitatively scored Ki67 by ImmunoRatio, and CD31 by positively stained cell numbers. Cell specific ESR1 and PGR positive cells were counted and the percentage (positive cells/total cells) is shown. ImmunoRatio calculates the percentage of positively stained nuclear cells/total cells.