A, C,&E. Expression analysis of IFN-γ, IL-17A, and IL-10 in C5L2−/− and wild type mouse ears following sensitization and challenge with OX or vehicle (control) by quantitative PCR. Results are normalized to β-actin, mean ± SEM for 6–9 mice/group. Significance of differences is indicated. B, D, F–H. Cytokine levels for IFN-γ, IL-17A, IL-10, IL-5 and IL-12 in C5L2−/− and wild type mouse ears following sensitization and challenge with OX or vehicle (control) determined by ELISA. Results are the mean ± SEM for 9–10 mice/group. Significance of differences is indicated.