Table 1.
Patient Characteristics at the Index Visit
| Total Cohort (N=152) | Non-obese (N=101) | Obese** (N=51) | P value | |
|---|---|---|---|---|
| Age, years | 49 (22, 69) * | 50 (22, 68) | 49 (31, 69) | 0.82 |
| Gender, Male (%) | 129 (85%) | 94 (94%) | 35 (69%) | <0.0001 |
| Education, years | 13 (7, 20) | 13 (7, 18) | 13 (9, 20) | 0.43 |
| Ethnicity/Race | ||||
| White (%) | 79 (52%) | 53 (52%) | 26 (51%) | 0.86 |
| Hispanic (%) | 22 (14%) | 12 (12%) | 10 (20%) | 0.20 |
| African American (%) | 48 (32%) | 35 (35%) | 13 (25%) | 0.25 |
| Comorbid Conditions | ||||
| Tobacco exposure ever (%) | 120 (79%) * | 78 (77%) | 42 (82%) | 0.47 |
| IV drug use ever (%) | 38 (25%) | 39 (29%) | 9 (18%) | 0.14 |
| Alcohol exposure | 4.0 (2.7, 7.6) | 4.0 (2.5, 7.3) | 4.2 (2.9, 7.6) | 0.67 |
| HCV antibody positive | 42 (26%) | 28 (26%) | 14 (25%) | 0.92 |
| Body mass index kg/m2 | 25.4 (17.3, 41.1) | 23.6 (17.3, 31.1) | 30.9 (22.0, 41.1) | N/A |
| WC for men, cm | 94 (71, 140) | 90 (71, 101) | 108 (102, 140) | N/A |
| WC for women, cm | 94 (75, 133) | 78 (75, 85) | 96 (88, 133) | N/A |
| Diagnosis of diabetes (%) | 15 (10%) | 9 (9%) | 6 (12%) | 0.58 |
| HIV Disease Status | ||||
| AIDS CDC diagnosis | 114 (75%) | 78 (77%) | 36 (71%) | 0.37 |
| Duration of HIV, years | 14.9 (1.5, 29.5) | 15.5 (2.7, 28.6) | 14.5 (1.5, 29.5) | 0.43 |
| Current CD43, cells/mm3 | 549 (65, 3199) | 504 (65, 1869) | 612 (75, 3199) | 0.04 |
| Nadir CD43, cells/mm3 | 117 (0, 816) | 101 (0, 816) | 155 (0, 369) | 0.57 |
| Plasma VL, c/mL (log10) | 1.7 (1.6, 3.0) | 1.7 (1.6, 3.0) | 1.6 (1.6, 2.6) | 0.03 |
| Plasma VL, undetectable | 124 (82%) | 80 (79%) | 44 (86%) | 0.29 |
| CSF VL, c/mL (log10) | 1.7 (1.6, 3.5) | 1.7 (1.6, 3.5) | 1.6 (1.6, 2.5) | 0.04 |
| CSF VL detectable (%) | 10 (7%) | 8 (8%) | 2 (4%) | 0.35 |
| Currently on ARV (%) | 151 (99%) | 100 (99%) | 51 (100%) | 0.66 |
| Duration of current ARV mo. | 26 (13-42) | 26 (15, 42) | 26 (12, 42) | 0.79 |
| Neurocognitive Impairment | ||||
| Global deficit score (GDS) | 0.21 (0.00, 2.36) | 0.14 (0.00, 2.36) | 0.29 (0.00, 1.93) | 0.04 |
| No. with HAND (%) | 43 (28%) | 21 (21%) | 22 (43%) | 0.004 |
*
Median (first and third quartiles) or frequency (percentage)
**
Waist circumference ≥88cm for women and ≥102cm for men