Table 2.
Clinical characteristics of the study patients | General population of term asphyxiated newborns treated with hypothermia (n = 145) | Term asphyxiated newborns treated with hypothermia and developing IVH (n = 15) | p value | IVH limited to the choroid plexus vessels in the lateral ventricles or IVH without ventricular dilatation (n = 8) | IVH with ventricular dilatation or parenchymal hemorrhage (n = 7) | p value |
---|---|---|---|---|---|---|
Gestational age (weeks), mean ± SD | 39.2 ± 1.5 | 39.1 ± 1.7 | NS | 39.5 ± 1.9 | 38.6 ± 1.3 | NS |
Birth weight (g), mean ± SD | 3420 ± 652 | 3274 ± 659 | NS | 3422 ± 673 | 3091 ± 590 | NS |
Gender, n (%) | NS | 0,007 | ||||
Male, n (%) | 78 (54) | 9 (60) | 2 (25) | 7 (100) | ||
Female, n (%) | 67 (46) | 6 (40) | 6 (75) | 0 (0) | ||
Apgar score < 5 at 10 min, n (%) | 74 (51) | 8 (53) | NS | 7 (88) | 5(71) | NS |
Arterial cord pH, mean ± SD | 6,99 ± 0.20 | 7.03 ± 0.16 | NS | 7.00 ± 0.16 | 7.06 ± 0.16 | NS |
Initial postnatal blood gas pH, mean ± SD | 7.03 ± 0.19 | 7.07 ± 0.16 | NS | 7.09 ± 0.12 | 7.06 ± 0.19 | NS |
Highest lactate level (mmol/L), mean ± SD | 9.12 ± 5.67 | 10.02 ± 5.53 | NS | 9.36 ± 4.70 | 10.77 ± 6.66 | NS |
Abbreviations: IVH intraventricular hemorrhage, NS non-significant