Table 2.

Fractal dimension value of normal and cancer tissues

No.	1		2			3			4			5			6			7
	FD		PR			PVR			AUS1			AUS2			FWHM			Combination
	Nor	Can	Sn.	Sp.	Cpoint	Sn.	Sp.	Cpoint	Sn.	Sp.	Cpoint	Sn.	Sp.	Cpoint	Sn.	Sp.	Cpoint	Sn.	Sp.
1	1.73	1.90	89.2	81.5	1.45	61.2	69.3	1.46	84.5	84.6	285	64.4	56.9	133	75.3	81.6	67	91.7	85.4
2	1.72	1.82	83.5	87.2	1.52	78.5	60.3	1.51	81.3	92.1	275	74.4	49.5	144	78.9	45.8	64	88.3	80.3
3	1.57	1.88	98	90.1	1.94	98.9	90.1	1.71	82.5	70.1	303	81.1	73.9	130	82.2	70.1	57.5	96.4	88.2
4	1.69	1.78	60.1	72.4	1.65	49.8	70.1	2.21	84.2	80.3	234	66.2	78.1	126	82.5	98.3	50.8	82.3	97.6
5	1.24	1.80	80.1	68.2	2.01	49.8	80.3	1.68	67.5	78.4	219	98	98.5	151	96.5	94.3	77	96.5	95.3
6	1.65	1.85	79.6	56.4	1.45	80.2	50.1	1.98	89.6	90.1	235	68.7	71.9	120	66.5	51.2	60.7	95.1	93.2
7	1.66	1.97	77.9	68.5	1.68	92.3	88.9	1.09	79.6	77.5	211	80.3	71.4	110	89.2	80.3	42	86.3	83.4
8	1.68	1.85	70.3	67.9	2.27	80.3	77.5	1.33	88.6	87.3	203	72.3	46.4	124	76.5	80.3	70	90.3	90.1
9	1.59	1.89	66.7	59.1	2.19	67.1	77.2	1.54	40.8	65.1	203	94.3	92.3	130	91.6	88.2	73	95.4	89.6
10	1.66	1.86	81.3	80.5	2.82	70.2	68.5	1.9	79.1	66.4	186	70.2	65.2	114	70.1	50.3	58.3	84.2	80.2
11	1.5	1.76	79.1	67.4	2.67	82.1	80.1	1.44	45.2	77.1	199	81.6	86.7	122	83.5	70.1	71	80.2	87.4
12	1.58	1.91	82.1	80.4	1.38	79.4	67.1	1.75	87.6	85.3	262	77.6	58.9	122	81.3	70.5	55.3	88.5	82.1
13	1.34	1.92	89.1	50.6	1.62	88.3	80.1	1.88	88.1	78.4	222	78.3	45.2	156	97.1	99.3	56	92.3	80.2
14	1.26	1.87	89.3	70.1	1.73	80.2	84.3	1.45	79.2	62.1	256	88.5	49.7	145	80.2	81.2	76	89.5	90.1
15	1.35	1.86	80.1	85.8	1.48	72.3	68.4	1.60	88.3	90.1	292	80.1	42.3	166	99	92.1	72	96.3	89.1
16	1.56	1.82	79.4	40.5	2.33	68.3	67.3	1.45	80.2	94.1	222	98.3	88.4	187	70.3	68.5	66	91.2	80.1
17	1.67	1.93	80.2	60.1	1.67	92.3	91.4	1.43	88.1	89.6	201	40.5	40.1	131	39.6	76.4	58	86.3	88.9
18	1.62	1.82	79.2	50.1	1.31	90.7	88.6	1.55	90.3	87.2	254	88.3	66	143	90.2	96.4	70	92.3	94.5
19	1.65	1.86	70.2	78.3	1.58	88.3	90.2	1.38	89.4	90.2	223	80.2	81.4	129	88.2	78	60	92.1	88.5
20	1.34	1.90	88.1	79.3	1.41	50.2	50.6	1.43	84.3	83.2	234	90.1	59.1	156	90.2	80.4	62	88.2	89.4
21	1.23	1.91	60.1	84.2	1.91	56.4	87.4	1.33	88.6	90.2	200	56.4	67.3	133	80.7	82.3	55	90.3	80.2
22	1.32	1.95	87.3	89.2	1.21	70.2	78.5	1.67	70.2	74.5	224	60.3	59.7	145	80.2	38.5	78	85.4	88.5
23	1.72	1.78	50.2	71.3	1.23	80.2	89.4	1.45	55.4	68.3	267	79.1	70.2	165	69.3	80.1	80	86.2	80.1
24	1.56	1.80	85.3	92.1	1.58	95.6	88.3	1.49	80.1	80.1	256	77.5	80.2	158	78.1	89.1	68	90.1	92.3
25	1.45	1.82	67.1	80.3	1.78	88.4	70.1	1.23	87.2	90.1	203	88.2	89.3	129	90.1	65.1	48	89.1	90.2
26	1.33	1.84	80.3	98.2	1.21	88.3	89.4	1.44	99.4	98.3	278	80.2	88.1	162	77.1	80.2	72	90.4	93.1
27	1.56	1.87	80.1	81.2	1.24	49.1	44.3	1.11	30.4	99.2	245	50.1	82.1	121	74.1	86.2	66	85.3	84.3
28	1.67	1.97	84.1	90	2.34	95.2	92.1	1.23	80.2	80.1	234	80.1	80	145	78.4	72.1	48	99.7	93.2
29	1.56	1.95	88.3	85.2	1.72	90.2	97.2	1.09	87.3	87.5	241	86.9	89.3	111	49.2	77.1	56	90.2	91.4
Mean	1.533	1.866	78.3	74.7	1.74	77	77.1	1.51	78.5	82.7	236.8	76.9	69.9	138.2	79.5	76.6	63.4	90	87.8
STD	0.1608	0.058	10.36	14.14	0.43	15.25	13.83	0.26	16.08	9.78	285	13.52	16.68	18.76	12.95	15.28	9.84	4.53	5.21

Sensitivity, specificity, and cut-off point of spectrum-based methods for distinguishing normal and cancer cells of 29 patients for training

AUS1 area under spectral curve normalized by the intensity of peak 1, AUS2 area under spectral curve normalized by the intensity of peak 2, FD fractal dimension, FWHM full width at half maximum of spectral curve, PR peak ratio, PVR peak and valley ratio, Sn sensitivity, Sp. specificity, Cpoint cut-off point of each sample, STD standard deviation