Table 2.
Relationship of Hoxd10 expression with pathological parameters of tumor
| Clinical parameters | HOXD10 | |||
|---|---|---|---|---|
| Low | High | t/χ 2 | P | |
| Age (years) | 59.77 ± 12.44 | 58.48 ± 11.85 | 1.107 | 0.269 |
| Gender | 0.519 | 0.4771 | ||
| Male | 135 (43.4 %) | 176 (56.6 %) | ||
| Female | 59 (47.2 %) | 66 (52.8 %) | ||
| Location | 4.379 | 0.112 | ||
| Proximal | 31 (56.4 %) | 24 (43.6 %) | ||
| Middle | 74 (45.4 %) | 89 (54.6 %) | ||
| Distal | 89 (40.8 %) | 129 (59.2 %) | ||
| Size | 25.716 | 0.0001 | ||
| <5 cm | 88 (34.4 %) | 168 (65.6 %) | ||
| ≥5 cm | 106 (58.9 %) | 74 (41.1 %) | ||
| Lauren classification | 63.165 | 0.0001 | ||
| Intestinal | 58 (26.0 %) | 165 (74.0 %) | ||
| Diffuse | 136 (63.8 %) | 77 (36.2 %) | ||
| Histology classification | 7.343 | 0.062 | ||
| Papillary adenocarcinoma | 3 (18.8 %) | 13 (81.2 %) | ||
| Tubular adenocarcinoma | 142 (43.6 %) | 184 (56.4 %) | ||
| Mucinous adenocarcinoma | 17 (58.6 %) | 12 (41.4 %) | ||
| Signet-ring cell carcinoma | 32 (49.2 %) | 33 (50.8 %) | ||
| Histologic differentiation | 5.25 | 0.154 | ||
| Well | 3 (23.1 %) | 10 (76.9 %) | ||
| Moderately | 50 (39.1 %) | 78 (60.9 %) | ||
| Poorly | 140 (47.8 %) | 153 (52.2 %) | ||
| Others | 1 (50.0 %) | 1 (50.0 %) | ||
| Invasion depth | 33.892 | 0.0001 | ||
| T1 | 9 (15.8 %) | 48 (84.2 %) | ||
| T2 | 39 (35.8 %) | 70 (64.2 %) | ||
| T3 | 129 (52.9 %) | 115 (47.1 %) | ||
| T4 | 17 (65.4 %) | 9 (34.6 %) | ||
| TNM stages | 60.859 | 0.0001 | ||
| I | 17 (18.9 %) | 73 (81.1 %) | ||
| II | 30 (28.8 %) | 74 (71.2 %) | ||
| III | 102 (59.0 %) | 71 (41.0 %) | ||
| IV | 45 (65.2 %) | 24 (34.8 %) | ||
| Lymphatic metastasis | 45.165 | 0.0001 | ||
| No | 40 (24.1 %) | 126 (75.9 %) | ||
| Yes | 154 (57.0 %) | 116 (43.0 %) | ||
| Regional lymph nodes | 51.95 | 0.0001 | ||
| PN0 | 40 (24.1 %) | 126 (75.9 %) | ||
| PN1 | 67 (49.3 %) | 69 (50.7 %) | ||
| PN2 | 65 (65.7 %) | 34 (34.3 %) | ||
| PN3 | 22 (62.9 %) | 13 (37.1 %) | ||
| Distant metastasis | 14.821 | 0.0001 | ||
| No | 153 (40.8 %) | 222 (59.2 %) | ||
| Yes | 41 (67.2 %) | 20 (32.8 %) | ||