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. 2015 Aug 28;6:176. doi: 10.3389/fphar.2015.00176

Table 2.

Kampo medicines for BMS, glossalgia, and AFP.

Target and Kampo medicine Effect
1) Nervous system
Saikokaryukotuboreito
Ameliorates chronic stress-induced depressive state by preventing prefrontal cortex dysfunction
1) Nervous system
Yokukansan
Antiallodynic effects in rats related to blockade of spinal cord glutamatergic neurotransmission via activation of glutamate transporters
1) Nervous system
Saibokuto
Improves glossodynia more effectively than diazepam plus vitamin B complex
2) Hot/cold, microcirculation
Hochuekkito
Improves symptoms of BMS by correcting “Ki deficiency”
2) Hot/cold, microcirculation
Tokishakuyakusan
Improves the symptoms of BMS by correcting deficiency of “Ketsu” and microcirculation
2) Hot/cold, microcirculation
kamishouyousan
Improves “Yo” by correcting ”kidney Yin” and “liver Yin” deficiency, as well as restless organ disorder based on Yin deficiency of five viscera
2) Hot/cold, microcirculation
Byakko-ka-ninjinto
Improves BMS symptoms such as dry mouth and intraoral pain
2) Hot/cold microcirculation
Kikyoto
Improves glossodynia and erythrokeratoderma
3) Kampo theory
Rikkunshito
Improves “spleen vital energy” and “heart Yin” deficiency, stagnation of “liver Ki (vital energy) producing fire,” and “gallbladder Ki (vital energy)” deficiency
3) Kampo theory
Jiinkokato, Hachimijiogan, Ryutanshakanto
Improves “spleen Yin” and “heart Yin” deficiency, “kidney Yo” deficiency, and “liver Ki (vital energy)” stagnation producing heart syndrome
3) Kampo theory
Seishoekkito, Bakumondoto
Improves “spleen Ki (vital energy) “ deficiency and “stomach Yin” deficiency producing heart syndrome
3) Kampo theory
Bakumondoto
Improves “spleen Ki” deficiency and “stomach Yin” deficiency producing heart syndrome
3) Kampo theory
Kamikihito, Chikujountanto
Improves “spleen Ki” and “heart Yin” deficiency, stagnation of “liver Ki producing fire,” and “gallbladder Ki” deficiency
3) Kampo theory
Rokumijiougan, Kanbakutaisoto
Improves Yo rise based on “kidney Yin” and “liver Yin” deficiency as well as restless organ disorder based on Yin deficiency of five viscera
3) Kampo theory
Hangeshashinto, Anchusan
Improves “spleen Yo” deficiency
3) Kampo theory
Mibakuekkito, Seinetsuhokito
Improves glossodynia