Table 4.
Kampo medicine in cancer treatment.
| Kampo medicine | Effects of Kampo medicine |
|---|---|
| Chingwaysan (CWS) | Effectively treats intraoral ulcerative lesions and gingival bleeding |
| Inhibits proliferation and induces apoptosis of tumor cells | |
| Increases Bax expression | |
| Danshen | Inhibits OSCC proliferation |
| Inhibits angiogenesis by downregulating multiple angiogenic genes | |
| Ninjinyoeito (NYT) | Reduces nausea/vomiting and bowel movement abnormalities |
| Improves motivation and fatigue/malaise | |
| Antioxidant effect | |
| Rikko-san (RKS) | Pain control via local anesthesia/analgesia |
| Antioxidant effect | |
| Byakkokaninjinto (BNT) | Useful for reducing symptoms of stomatitis and xerostomia induced by radiotherapy. |
| Keishikajutsubuto (KJT) | Improves radiation-induced neuralgia (cold type) |
| Hochuekkito (HET) | Improves immune function and appetite in elderly patients |
| Antioxidant effect | |
| Slows wasting and improves QOL. | |
| Rikkunshito (RKT) | Contributes to the amelioration of anorectic conditions in cancer cachexia-anorexia syndrome |
| Orengedokuto (OGT) | Improves mucositis caused by anticancer agents |
| Antioxidant effect | |
| Juzentaihoto (JTT) | May increase long-term survival |
| May induce spontaneous regression of tongue cancer | |
| Inhibits the progression of tumors |