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. 2015 Jul 22;43(15):7207–7216. doi: 10.1093/nar/gkv757

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Structural changes induced by mutations of V149. (A) The structure alignment of WT-RNP and V149G-RNP. The side chain of V149 (WT-RNP) is shown in red (meshed surface) and the side chain of G149 is shown in green (solid surface). (B) The distance between the mass center of target U and the C_γ atom of D85: WT-RNP (black) and V149G-RNP (red). (C) The distance between the mass center of target U and the C_γ atom of D85: WT-RNP (black) and V149L-RNP (red).