Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Formation of a hole at the entrance of the active site in the product complex. After U (left) is modified to Ψ (right), the conformation of the active site is changed accordingly which is induced by the rotation of the sugar ring of Ψ. A hole is formed at the entrance of the active site, allowing the water molecules to enter. The residues near the active site are presented with yellow surfaces and the loop is showed with red ribbon.
