Figure 2. GADD34 -deficient mice accumulated a fat in liver with aging.

(a) Sections of the liver of 15 M old male WT (upper) and GADD34 -deficient (lower) mice were stained with H&E, Masson’s trichrome and Oil Red O. (b) Bone marrow cells were stained with anti-CD24, Sca-1 and CD34 antibodies. Graph (right) shows CD24⁺/Sca-1⁺/CD34⁺ adipocyte progenitor cells in bone marrow. Representative results of three independent experiments are shown. Data shown are the mean ratio ± SEM. (*p < 0.05).